Peptide Active Data Details
Basic Peptide Information
DICL ID
DICL_Pep_06405
Ion Channel
Neuronal acetylcholine receptor subunit alpha-2/beta-2
Peptide Function
Antagonist
Gene Name
CHRNA2/CHRNB2
Activity Data (nM)
IC50
2990 nM
Ki
Not available
EC50
Not available
Kd
Not available
Biologically Active
Not specified
Sequence Information
Peptide Sequence
TARSSGRYCRSPYDRRRRYCRRITDAAV
Peptide UniProt Accession
Not available
UniParc
Not available
Peptide Synonyms/Alias
[CHEMBL4577696; BDBM50520493]
Peptide Species
Not specified
Peptide Name
Not available
CAS Number
Not available
Experimental Conditions
pH
pH 7.4
Holding Potential (mV)
−70 mV
Temperature
18 °C
Test Method
Patch-clamping
Test Species
Xenopus laevis oocyte
Binding Information
Binding Site
Extracellular domain
Binding Site Residue
Not specified
Ion Channel Information
Gene Abbreviation (ABB)
nAChRs
Ion Channel UniProt Accession
Source Organism
Homo sapiens (Human)
References & Disease Information
Disease
Not specified
PubChem CID
URL
Not available
PMID
Patent
Not available